The Dynamic Skeletal Muscle Organ

Publication Date: 09 September 2017

Presenter(s): Josep M Argilés, PhD

Location:The Hague, The Netherlands

The Dynamic Skeletal Muscle Organ That Orchestrates Whole Body Metabolism

Dr Argilés describes the role of skeletal muscle as one of the key regulators of energy and protein metabolism by way of metabolic crosstalk between body organs. Skeletal muscle orchestrates metabolic events, regulates metabolic homeostasis, and serves as an important thermogenic and endocrine organ. He highlights that acute and chronic diseases, often accompanied by decreased dietary intake and increased metabolic needs, lead to muscle loss associated with sarcopenia and cachexia, resulting in a variety of adverse health events. Dr Argilés concludes that the combination of nutritional approaches and exercise has important potential in treatment of muscle wasting.

Presenter Bio(s):

Josep M. Argilés, PhD

Professor, Biochemistry & Molecular Biology of Cancer 
Universitat de Barcelona 
Barcelona, Spain

Professor Josep M. Argilés was born in Barcelona, Catalonia, Spain, and completed his undergraduate studies in Biology at the University of Barcelona, graduating with a First Class Honours Degree and Special Prize for the best B.Sc. He received his Doctorate in Biochemistry from the same university with Cum Laude, obtaining the Prize for the best doctorate of that year. He then became a Lecturer in Biochemistry and carried out postdoctoral work on acetone metabolism in mammals. He undertook further postdoctoral training in the Laboratory of Metabolism and Molecular Biology at the National Institutes of Health, Bethesda, Maryland. He later became a full professor of biochemistry and molecular biology of cancer at the Faculty of Biology, University of Barcelona, where he led a research group interested in cancer cachexia. His main contribution to the field of cancer research concerns the mechanisms associated with cancer cachexia.

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